Researchers discover that Tirzepatide (Mounjaro) weight loss injection not only reduces appetite, but also activates brown adipose tissue, i.e. it stimulates a type of fat that specializes in ‘burning’ calories from food, in a new study in mice.

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Steve Borthwick is ready to radically overhaul his misfiring England side for the Six Nations clash against Italy on Saturday, with Fin Smith expected to be handed the No 10 jersey.

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