Klenerman and Balasubramanian’s great insight was that template DNA could be sequenced by synthesizing a complementary strand of reversible terminators; basically, extending the chain one base at a time and determining the identity of each nucleotide by looking at the color of its fluorophore. In 1998, the pair started a company called Solexa to develop the technology.
过去,“零负团费”模式迫使导游成为销售员,损害了游客体验与行业声誉。携程力推的“大团变小团”变革,通过定制游、私家团等产品,将市场导向服务与体验的竞争。
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